TREATMENT OF BRONCHIAL ASTHMA: PHARMACOLOGICAL AND NON PHARMACOLOGICAL APPROACHES
Keywords:
Bronchial asthma, airway inflammation, inhaled corticosteroids, bronchodilators, asthma management, exacerbation prevention, patient education.Abstract
Bronchial asthma is a chronic inflammatory disorder of the airways characterized by reversible airflow obstruction, bronchial hyperresponsiveness, and recurring episodes of wheezing, shortness of breath, chest tightness, and coughing. Effective management of asthma requires a combination of pharmacological therapy, patient education, and lifestyle modifications to achieve symptom control, prevent exacerbations, and improve quality of life. Pharmacological interventions include inhaled corticosteroids, bronchodilators, leukotriene receptor antagonists, and biologic agents, while non-pharmacological approaches involve allergen avoidance, smoking cessation, and regular monitoring. This article provides an overview of current strategies for the treatment of bronchial asthma, focusing on individualized patient care and evidence-based management.
References
1. Global Initiative for Asthma (GINA). Global Strategy for Asthma Management and Prevention, 2024 Update.
2. Reddel H.K., Bacharier L.B., Bateman E.D., et al. Global Initiative for Asthma Strategy 2022: Executive Summary and Key Recommendations. The Lancet, 2022;399:123–135.
3. Holgate S.T. Pathophysiology of Asthma: Insights from Molecular Biology. Allergy, 2011;66:278–289.
4. Bateman E.D., Hurd S.S., Barnes P.J., et al. Global Strategy for Asthma Management and Prevention: GINA Executive Summary. European Respiratory Journal, 2008;31:143–178.
5. Wenzel S.E. Severe Asthma: From Phenotypes to Personalized Medicine. The Lancet, 2012;380:1371–1381.
6. Castro M., Corren J., Pavord I.D., et al. Dupilumab Efficacy and Safety in Moderate-to-Severe Uncontrolled Asthma. New England Journal of Medicine, 2018;378:2486–2496.
7. National Heart, Lung, and Blood Institute (NHLBI). Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma, 2007.
