QUTIRISH (RABIES) KASALLIGIDA MARKAZIY NERV TIZIMI NEVRONLARI VA STRUKTURAVIY ANATOMIYASINING PATO-MORFOLOGIK OʻZGARISHLARI

Authors

  • Qobilov Ozodbek Sherali oʻgʻli University of Business and Science Davolash ishi yo‘nalishi 25-14 guruh talabasi Author
  • Sadirdinov Shohjahon Husanboy oʼgʻli University of Business and Science Davolash ishi yo‘nalishi 25-14 guruh talabasi Author
  • Yoʻldasheva Margʻuba Davlatmirza qizi University of Business and Science Davolash ishi yo‘nalishi 25-14 guruh talabasi Author
  • Rayimov Ogʻabek Oybek oʼgʻli University of Business and Science Davolash ishi yo‘nalishi 25-14 guruh talabasi Author
  • Tursunpoʻlatov Murodjon Mirzohidjon oʻgʻli University of Business and Science Davolash ishi yo‘nalishi 25-14 guruh talabasi Author
  • Toxirova Madina Sanat qizi University of Business and Science Davolash ishi yo‘nalishi 25-14 guruh talabasi Author

Keywords:

qutirish kasalligi, rabies virusi, neyroanatomis, Negri tanachalari, ammon shoxi, neyronal destruksiya, aksonal transport, ensefalomielit

Abstract

Ushbu maqolada qutirish kasalligi (rabies ensefaliti) davomida markaziy nerv tizimi (MNT) anatomik va gistologik tuzilmalarida sodir bo‘ladigan pato-morfologik va destruktiv o‘zgarishlar tahlil qilingan. Rabies virusining neyrotrop xususiyatlari, uning retrograd aksonal transport orqali bosh miya va orqa miya tuzilmalariga tarqalish mexanizmlari yoritilgan. Tadqiqot davomida ammon shoxi (gippokamp), po‘stloq neyrallari va purkinye hujayralarida o‘ziga xos patognomonik tuzilmalar — Negri tanachalari shakllanishining anatomik qonuniyatlari hamda neyronal apoptoz jarayonlari klinik-gistologik jihatdan asoslab berilgan.

References

1. Jackson, A. C. (2018). Human Rabies: a Clinical Review. Current Infectious Disease Reports, 20(9), 32-39.

2. Hemachudha, T., Ugolini, G., Wacharapluesadee, S., et al. (2013). Human rabies: neuropathogenesis, diagnosis, and management. The Lancet Neurology, 12(5), 498-513.

3. Fooks, A. R., Cliquet, F., Finke, S., et al. (2017). Rabies. Nature Reviews Disease Primers, 3(1), 17091.

4. Ismoilov, U. K., & Saidov, M. S. (2023). Qutirish (rabies) ensefalitida markaziy nerv tizimining patologik anatomiyasi va gistomorfologik xususiyatlari. O‘zbekiston Tibbiyot Jurnali, 4(12), 52-58.

5. Raxmonov, A. T. (2024). Neyrotrop virusli infeksiyalarda bosh miya poyasi va uzunchoq miya yadrolarining destruktiv o‘zgarishlarini qiyosiy baholash. Tibbiyotda Yangi Kun, 2(49), 140-146.

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Published

2026-06-15

Issue

Vol. 3 No. 3 (2026): STUDYING THE PROGRESS OF SCIENCE AND ITS SHORTCOMINGS

Section

Articles