TOKSOPLAZMOZ: PATOGENEZ, KLINIK SHAKLLARI VA ZAMONAVIY DIAGNOSTIKA YONDASHUVLARI
Keywords:
toksoplazmoz, Toxoplasma gondii, parazitar infeksiya, konjenital zararlanish, immun javob, miya ensefaliti, serologik diagnostika, PZR, avidlik testi, xorioretinit.Abstract
Toksoplazmoz — Toxoplasma gondii tomonidan chaqiriladigan, dunyoda eng keng tarqalgan obligat hujayra ichki parazitar kasalliklardan biridir. U asosan immuniteti pasaygan shaxslar va homilador ayollar uchun jiddiy klinik ahamiyatga ega. Parazit organizmga kirgach, hujayra ichida maxsus parazit vakuolasi hosil qiladi va mezbon immun javobidan qisman himoyalanadi. Tadqiqotlar shuni ko'rsatadiki, dunyo aholisining 30–50% qismi ushbu infeksiya bilan zararlangan. Maqolada toksoplazmozning molekulyar patogenezi, transplatsentar yuqish mexanizmi, markaziy asab tizimi zararlanishi, klinik shakllari hamda zamonaviy laborator diagnostika usullari ilmiy asosda tahlil qilingan. Shuningdek, epidemiologik ko'rsatkichlar, xavf guruhlari va profilaktika choralari yoritilgan
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