EFFECT OF 6-AMINOPURINE HYDROGEL ON THE FORMATION OF GRANULATION TISSUE
Keywords:
granulation tissue, 6-aminopurine, hydrogel, wound healing, tissue regeneration.Abstract
Granulation tissue formation is a key stage in the wound healing process, characterized by fibroblast proliferation, angiogenesis, and extracellular matrix deposition. The present study investigates the influence of a 6-aminopurine-loaded hydrogel on the formation of granulation tissue in damaged skin. The hydrogel system provides a moist environment and ensures controlled release of the biologically active compound. Experimental observations showed that the use of the hydrogel significantly accelerated fibroblast proliferation, increased vascularization, and promoted collagen deposition in the wound area. These results indicate that the combination of hydrogel matrices and purine derivatives can effectively stimulate tissue regeneration and improve wound healing outcomes.
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