THE IMPACT OF OBESITY ON THE DEVELOPMENT OF CARDIOPATHIES AMONG THE POPULATION OF UZBEKISTAN
Keywords:
Obesity; Cardiopathies; Cardiovascular diseases; Risk factors; Hypertension; Public health; Uzbekistan; Prevention; Lifestyle; Metabolic syndrome.Abstract
Obesity has become one of the leading public health challenges in Uzbekistan, with significant implications for cardiovascular health. This article examines the relationship between obesity and the development of cardiopathies among the Uzbek population. The study explores epidemiological data, physiological mechanisms, and social determinants contributing to the growing prevalence of obesity. The analysis highlights that obesity is strongly correlated with hypertension, ischemic heart disease, and cardiac failure through mechanisms such as insulin resistance, dyslipidemia, and chronic inflammation.Moreover, sedentary lifestyles and high-calorie diets have accelerated the rise in obesity across different age groups. The article concludes that effective prevention and early intervention are crucial for mitigating cardiovascular risks. National strategies should focus on promoting healthy eating, physical activity, and regular medical screening to reduce the burden of obesity-related cardiopathies in Uzbekistan.
References
1. World Health Organization. Obesity and Overweight: Key Facts. WHO, 2024.
2. Ministry of Health of the Republic of Uzbekistan. National Report on Noncommunicable Diseases and Risk Factors. Tashkent, 2023.
3. Yusuf, S., et al. “Obesity and Cardiovascular Disease: Pathophysiologic Insights and Epidemiology.” European Heart Journal, vol. 43, no. 5, 2022, pp. 578–588.
4. Popkin, B. M., & Ng, S. W. “The Nutrition Transition and Obesity in the Developing World.” Public Health Nutrition, vol. 25, 2023, pp. 1–9.
5. Akhmedova, D. K., & Karimov, B. T. “Lifestyle and Metabolic Risk Factors in Urban and Rural Populations of Uzbekistan.” Central Asian Journal of Medicine, vol. 29, no. 2, 2022, pp. 45–52.
6. Lavie, C. J., et al. “Obesity and Cardiovascular Diseases: Implications Regarding Fitness, Fatness, and Severity in the Obesity Paradox.” Journal of the American College of Cardiology, vol. 72, 2018, pp. 234–247.
7. WHO Regional Office for Europe. Noncommunicable Diseases Country Profile: Uzbekistan. Copenhagen, 2023.
8. Eckel, R. H., et al. “Mechanisms of Obesity-Associated Cardiovascular Disease.” Circulation, vol. 144, no. 4, 2021, pp. 279–295.
9. Ng, M., et al. “Global, Regional, and National Prevalence of Overweight and Obesity in Children and Adults.” The Lancet, vol. 384, 2014, pp. 766–781.
