ATROF-MUHIT IFLOSLANISHINING BOLALAR SALOMATLIGIGA EPIGENETIK VA TOKSIKOLOGIK TA’SIRI
Keywords:
atrof-muhit, ifloslanish, bolalar, salomatlik, epigenetika, toksikologiya, genetik o‘zgarishlarAbstract
Ushbu maqolada atrof-muhit ifloslanishining bolalar salomatligiga bo‘lgan epigenetik va toksikologik ta’siri har tomonlama tahlil qilinadi. Bolalar o‘zlarining fiziologik va biologik xususiyatlari tufayli ekologik zararli omillarga nisbatan ancha sezuvchan qatlam sanaladi. Ularning genetik tuzilmasida yuzaga keladigan epigenetik o‘zgarishlar, jumladan DNK metilatsiyasi, histon modifikatsiyalari va mikroRNA faoliyati orqali sog‘liqda uzoq muddatli o‘zgarishlarga sabab bo‘ladi. Shu bilan birga, toksikologik ta’sirlar natijasida organizmda yallig‘lanishlar, allergik reaksiyalar, autoimmun holatlar va asab tizimi muammolari rivojlanadi. Maqolada ushbu xavfli omillarning mexanizmlari, oqibatlari va ularni kamaytirish yo‘llari ilmiy asosda tahlil qilinadi.
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