INNOVATIVE NANOTECHNOLOGIES IN MEDICINE
Keywords:
Nanomedicine, Nanotechnology in medicine, Targeted drug delivery, Biomedical nanomaterials, Molecular diagnostics, Cardiovascular diseases, Medical microchips, Antioxidant nanostructures, Modern medical technologies,Abstract
This article is written based on the analysis of modern scientific publications devoted to nanotechnologies in medicine, including materials from international research centers and medical institutions. Particular attention is paid to the possibilities of applying nanotechnologies in the healthcare system of the Republic of Uzbekistan.
References
1. M. Schena, D. Shalon, R. W. Davis, H. O. Brown. Quantitative monitoring of gene expression patterns with a complementary DNA microarray//Science. Vol. 270, № 5235. 1995.
2. M. Schena, D. Shalon, R. Heller et al. Parallel human genome analysis: microarraybased expression monitoring of 1000 genes//Proc. Natl. Acad. Sci. U.S.A. Vol. 93, № 20, 1996.
3. M. E. Truckenmiller, M. P. Vawter, C. Cheadle et al. Gene expression profile in early stage of retinoic acidinduced differentiation of human SHSY5Y neuroblastoma cells//Restor. Neurol. Neurosci. Vol. 18, № 2–3, 2001.
4. H. Suzuki, E. Gabrielson, W. Chen et al. A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer//Nat. Genet. Vol. 31, № 2, 2002.
5. R. A. Young. Biomedical discovery with DNA arrays//Cell. Vol. 102, № 1, 2000.
6. B. J. Hong, V. Sunkara, J. W. Park. DNA microarrays on nanoscale controlled surface. Nucleic Acids Res. Jul 7, 2005.
7. B. N. Gosalia, S. L. Diamond. Printing chemical libraries on microarrays for fluid phase nanoliter reactions. Proc Natl Acad Sci USA. July 22, 2003.
8. Y. P. Bao, M. Huber, T. F. Wei, S. S. Marla, J. J. Storhoff, U. R. Mueller. SNP identification in unamplified human genomic DNA with gold nanoparticle probes. Nucleic Acids Res. Jan 19, 2005.
9. C. R. Sabanayagam, J. R. Lakowicz. Increasing the sensitivity of DNA microarrays by metalenhanced fluorescence using surface bound silver nanoparticles. Nucleic Acids Res. January, 2007.
10. R. S. Vasan. Biomarkers of Cardiovascular Disease Molecular Basis and Practical Considerations. Circulation. 2006.
11. А. А. Жлоба, С. Ю. Иванова. Изучение свойств и выявление экспрессии рецептора активтрованного альфа2макроглобулина человека//Клиническая лабораторная диагностика, № 4, 2002.
12. J. Ako, H. N. Bonneau, Y. Honda, P. J. Fitzgerald. Design criteria for the ideal drugeluting stent. Am. J. Cardiol, 2007.
13. G. Nakazawa, A. V. Finn, R. Virmani. Vascular pathology of drug eluting stents. 2007. 14. L. Y. Huang, M. C. Yang. Hemocompatibility of layerbylayer hyaluronic acid/heparin nanostructure coating on stainless steel for cardiovascular stents and its use for drug delivery. J. Nanosci.Nanotechnol, 2006.
15. B. Langeveld, A. J. Roks, R. A. Tio et al. Rat abdominal aorta stenting: a new and reliable small animal model for instent restenosis. 2004.
