TRANSMISSION OF LIVER DISEASES FROM GENERATION TO GENERATION

Authors

  • Bunyodjon Mamatvaliyev son of Rahmonali University of Business and Science "Lecturers in Human Anatomy at the Department of Medicine" Author
  • Jamolidinova Madina daughter of Fazlidin Student of the “University of Business and Science” Faculty of General Medicine, Group 25-01 Author
  • Toshaliyeva Husnida daughter of Mamasoli Student of the “University of Business and Science” Faculty of General Medicine, Group 25-14 Author
  • Toxirova Madina daughter of San’atjon Student of the “University of Business and Science”, Faculty of General Medicine, Group 25-14 Author
  • Xaydaraliyeva Mardona daughter of G’ulomjon Student of the “University of Business and Science”, Faculty of General Medicine, Group 25-08 Author
  • Axmadjonova Malika daughter of Olimjon Student of the “University of Business and Science”, Faculty of General Medicine, Group 25-07 Author

Keywords:

Liver diseases, hereditary diseases,genetic diseases, hemochromatosis, Wilson`s disease,disease,Gilbert`s syndrome, generational transmission, genetic meachanisms,prevention,clinical manifestations,genetic counseling liver function, copper accumulation.

Abstract

This article discussus the hereditary transmission of liver diseases from generation to generation.It presents information about the types of hereditary liver diseases their genetic mechanisms,and clinical manifestations.Additionally,detailed explanations are provided about common hereditary liver diseases such as hemochromatosis,Wilson’s disease, and gilbert syndrome.The article also explores early diagnosis and treatment methods for hereditary conditions,along with genetic counseling and preventive measures.It aims to establish a scientific foundation for understanding the genetic basis of liver diseases and develoing new therapeutic approaches.

References

1.Andrews, N. C., Schmidt, P. J., & Fleming, M. D. (2018). Hereditary hemochromatosis: Genetics, pathogenesis, diagnosis, and treatment. Hematology/Oncology Clinics of North America, 32(3), 495-507. https://doi.org/10.1016/j.hoc.2018.02.009

2 .Berg, J. M., Tymoczko, J. L., Gatto, G. J., & Stryer, L. (2020). Biochemistry (9th ed.). W.H. Freeman and Company. (Wilson disease and copper metabolism)

3 .Kumar, V., Abbas, A. K., & Aster, J. C. (2019). Robbins Basic Pathology (10th ed.). Elsevier. (A1-antitrypsin deficiency and genetic liver diseases)

4.European Association for the Study of the Liver (EASL) Clinical Practice Guidelines: Wilson's disease. Journal of Hepatology, 2012; 56(3): 671-685. https://doi.org/10.1016/j.jhep.2011.09.007.

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Published

2025-12-08