STRUCTURAL AND FUNCTIONAL RESPONSES OF THE THYROID GLAND TO CONCURRENT DEFICIENCY OF ESSENTIAL MICROELEMENTS (MG, FE, SE, ZN): A COMPARATIVE STUDY

Authors

  • O.G. Aslanov Independent Researcher, Department of Anatomy, clinical anatomy (OSTA), Bukhara State Medical Institute named after Abu Ali ibn Sino Author
  • R.R. Baymuradov Associate Professor, Department of Anatomy, clinical anatomy (OSTA), Bukhara State Medical Institute named after Abu Ali ibn Sino, PhD Author

Keywords:

thyroid gland, microelement deficiency, morphology, morphometry, microcirculation, follicle, thyrocyte, stroma, adaptation.

Abstract

This study presents a comparative morphological and morphometric analysis of the thyroid gland in white rats under combined deficiency of microelements (Mg, Fe, Se, Zn). Structural organization of thyroid follicles, colloid composition, stromal elements, and microcirculatory features were examined. The results indicate that microelement imbalance leads to decreased secretory activity of thyrocytes and induces compensatory-adaptive reactions within the stromal and vascular systems, reflecting the gland’s response to metabolic stress.

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Published

2025-11-17